Esomeprazole magnesium salt( —— )

Catalog No. M10711 CAS No. 1198768-91-0

A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Esomeprazole magnesium salt
Note

Research use only, not for human use.
Brief Description

A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells.
Description

A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells; the (S)-(?)-enantiomer of omeprazole for treatment of dyspepsia, peptic ulcer disease, and gastroesophageal reflux disease.Ulcer Approved.
In Vitro

Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification.Cell Viability Assay Cell Line:MDA-MB-468 cells Concentration:25 μM, 50 μM, 75 μM, 100 μM Incubation Time:20 hours Result:Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner.
In Vivo

Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification.Cell Viability Assay Cell Line:MDA-MB-468 cells Concentration:25 μM, 50 μM, 75 μM, 100 μM Incubation Time:20 hours Result:Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner.
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Proton Pump
Recptor

Proton Pump
Research Area

Other Indications
Indication

Ulcer

Chemical Information

CAS Number

1198768-91-0
Formula Weight

368.7126
Molecular Formula

C17H18MgN3O3S+
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC.[Mg]
Chemical Name

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (1:1)